Tuesday, 18 September 2012
What causes infertility in women?
- Most cases of female infertility are caused by problems with ovulation. Without ovulation, there are no eggs to be fertilized. Some signs that a woman is not ovulating normally include irregular or absent menstrual periods.
- Ovulation problems are often caused by polycystic ovarian syndrome (PCOS). PCOS is a hormone imbalance problem which can interfere with normal ovulation.
- PCOS is the most common cause of female infertility. Primary ovarian insufficiency (POI) is another cause of ovulation problems.
- POI occurs when a woman's ovaries stop working normally before she is 40. POI is not the same as early menopause.
Less common causes of fertility problems in women include:
- blocked Fallopian tubes due to pelvic inflammatory disease, endometriosis, or surgery for an ectopic pregnancy
- physical problems with the uterus
- uterine fibroids, which are non-cancerous clumps of tissue and muscle on the walls of the uterus.
Medical treatments
- Medical treatment of infertility generally involves the use of fertility medication, medical device, surgery, or a combination of the following.
- If the sperm are of good quality and the mechanics of the woman's reproductive structures are good (patent fallopian tubes, no adhesions or scarring), physicians may start by prescribing a course of ovarian stimulating medication.
- The physician may also suggest using a conception cap cervical cap, which the patient uses at home by placing the sperm inside the cap and putting the conception device on the cervix, or intrauterine insemination (IUI), in which the doctor introduces sperm into the uterus during ovulation, via a catheter.
- In these methods, fertilization occurs inside the body.
- If conservative medical treatments fail to achieve a full term pregnancy, the physician may suggest the patient undergo in vitro fertilization (IVF).
- IVF and related techniques (ICSI, ZIFT, GIFT) are called assisted reproductive technology (ART) techniques.
- ART techniques generally start with stimulating the ovaries to increase egg production.
- After stimulation, the physician surgically extracts one or more eggs from the ovary, and unites them with sperm in a laboratory setting, with the intent of producing one or more embryos.
- Fertilization takes place outside the body, and the fertilized egg is reinserted into the woman's reproductive tract, in a procedure called embryo transfer.
- Other medical techniques are e.g. tuboplasty, assisted hatching, and Preimplantation genetic diagnosis.
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