Sunday, 24 March 2019

How to choose the best IVF Center?


Why choose Femelife Fertility?

Femelife fertility, Chennai was started in 2010 and has spread its branches to Kolkata, Bhubaneswar, Tirupati, Pondicherry, Ambattur, Berhampur, Cuttack and Bangladesh in a short period of time. The main reason for its enormous growth is its popularity among fertility patients and doctors. This wide network also helps patients to avail high class fertility care at door step.

Initial visit at Femelife –

Usually at initial visit patients spend 30 to 45 minutes at our IVF Center. The receptionist and the staff are cordial and behave in a friendly manner. The patients are never made to wait for long time rather the appointment time is strictly followed. For patient’s convenience OPD hours are split into morning and evening sessions. This makes working couple not to lose duty hours.


Counselling at Femelife -

Our patient counsellors are highly skilled and trained personnel having in depth knowledge about the fertility issues and experienced enough to handle the stressed couple. At the initial counselling both partners are investigated for the cause of infertility. The options of fertility treatment are discussed openly with the couple following ethical guidelines. Couple are encouraged to participate in the discussion, Basic knowledge about human reproduction is explained with visual aids.


FEMELIFE is widely recognised as the architect of modern IVF Treatment in India. Dr. Nabaneeta and her team have acquired special expertise in treating problems of IVF, laparoscopy, reproductive endocrinology, menopause, and infertility. Best Fertility Doctors and embryologists are available for ICSI, IVF, Infertility treatment and PCOS management. We are among the best IVF hospitals for Egg donation, Embryo donation, Surrogacy, surrogate mother care, high risk pregnancy care, IUI, IVF and ICSI, PGD, Assisted hatching, cryopreservation and Karyotyping.


Natural conception at Femelife –

Not all the patients attending the IVF clinic need fertility treatment. Approximately 80% of couples will conceive in the first 6 months of attempting pregnancy. Fertility enhancement by natural methods are encouraged at Femelife. Lifestyle modifications like diet, exercise, avoiding smoking can improve fertility rates in young couples. Like many aspects of our health, fertility is improved by adopting a healthy lifestyle. Maintaining an ideal weight, a diet rich in antioxidants (found in fruits and vegetables), as well as multi-vitamins may improve the quality of egg and sperm. Avoiding pollution, smoking, junk food, reducing stress and controlling chronic medical conditions such as high blood pressure and diabetes may also improve a couple’s chances of fertility. Couples with underlying medical or genetic conditions are screened by doctors at Femelife so that they can increase their overall health before conceiving. Overweight men interested in optimizing fertility are encouraged to attain an ideal body weight before fertility treatment. Antioxidants such as vitamins E and C are supplemented which have been found to result in a slight increase in both sperm count and movement. Maintaining an ideal weight avoids PCOS {polycystic ovaries} hence improves the quality of egg and chances of ovulation. At Femelife we take care of your lifestyle before starting IVF programme.

IUI at Femelife –

Femelife runs a highly successful IUI programme due to the active customisation of protocols and selection of appropriate patient groups. Accurate follicular tracking, controlling the quality of eggs by use of fertility drugs and timing of IUI are crucial for our better success rates by IUI. We also run a down regulated IUI protocol which gives optimum success in PCOS patients.


IVF /ICSI at Femelife –

There are two ways that an egg may be fertilised in the laboratory: IVF and ICSI. In traditional IVF, 50,000 or more swimming sperm are placed next to the egg in a laboratory dish. Fertilisation occurs spontaneously when one of the sperm enters into the cytoplasm of the egg. In the ICSI process, a tiny needle, called a micropipette, is used to inject a single sperm into the center of the egg. Our experienced embryologists and excellent culture conditions in IVF laboratory have achieved 80-90 % fertilisation rate. We encourage blastocyst transfer for better success and to reduce multiple pregnancy rate.



Cryopreservation at Femelife IVF laboratory –

We have facilities for sperm, egg, embryos, ovarian tissue and testicular tissue. Patients proposed to undergo cancer therapy, transgender patients and women delaying pregnancy can benefit from cryopreservation. Our thawing rates for embryo, egg or sperm is one of the best in the country.

PGD/PGS options at our center –

Preimplantation genetic diagnosis (PGD) is a genetic test on cells removed from embryos, to help select the best embryo(s) for pregnancy or to make offspring free of a genetic disease.

PGD at Femelife is offered for 3 major groups of diseases:

(1) sex-linked disorders,
(2) single gene defects, and
(3) chromosomal disorders

Primary candidates for PGS at Femelife includes the following:

• Women of advanced maternal age
• Couples with history of recurrent pregnancy loss
• Couples with repeated IVF failure
• Male partner with severe male factor infertility





Care of IVF pregnancy at Femelife-

Every pregnancy is unique, and precious to the would be parents no matter how the baby is conceived. Pregnancy is well maintained by good luteal support and safe pregnancy tips. Patients are regularly screened for any signs of preterm labor, cervical incompetence, fetal wellbeing. They are screened for medical disorders and high risk pregnancy is taken care of. Facilities for newborn are also available under the care of neonatologists and skilled nurses.

IVF success at Femelife –

The high success rates at Femelife is contributed by our dedicated staff, doctors and embryologists. Our IVF success is reflected in our high take home baby rate, minimal biochemical pregnancy and reduced miscarriage rate. We have delivered above 5000 babies in our various centers during last 8 years and have helped the families to fulfil their dream.



24/7 fertility service available in Femelife, Chennai-

Some pregnancies become high risk as they progress, while some women are at increased risk for complications even before they get pregnant for a variety of reasons. For care of all these women Femelife Fertility provides 24/7 health care with trained nurses and doctors.



High IVF success rate, friendly approach and compassionate treatment makes FEMELIFE popular in this field among all. Furthermore, they have a wonderful health blog which takes care of healthy habits, encourages natural conceptions among patients. Hence Femelife Fertility is the best IVF Centre in Chennai, India.


Monday, 18 February 2019

Facts of follicular growth in Ovary






 
Follicles in the ovary of a girl child are not growing and are in the sleeping stage. They start growing cyclically once the girl attains menarche.














Follicles in the ovary grow progressively in the early half of menstrual cycle. In the later half they regress if pregnancy does not happen. If the woman falls pregnant the ovulated  follicle starts secreting hormones and maintains the pregnancy.



Each mature follicle contains an egg surrounded by cells called cumulus. Mature eggs have cumulus which are loosely bound where as immature eggs are surrounded by compact cumulus.




In IVF egg is collected by follicular aspiration. The egg which floats in the follicular fluid after HCG trigger is aspirated with its surrounding cumulus.




A mature egg only can be fertilised by a sperm. Mature egg has completed its cell growth and ready to fertilise with sperm. It has loosened it cumulus for easy entry of sperm. A healthy sperm can dissolve the wall of egg (called zona ) and enter inside.



Healthy sperms with good movement are essential to fertilise an egg. Sperms with rapid movement can travel upto the egg in the fallopian tube. They produce enzymes which can dissolve the zona pellucida and allow entry of a sperm.



In ultrasonic monitoring we can only see the follicle filled with fluid. Very small follicles in early days of menstruation can not be seen in ultrasound imaging. As the follicle grow they are filled with fluid and become visible in USG.



Human eggs are not visible to naked eye and can only be seen under microscope. Follicular monitoring can tell us about the number of follicles but not eggs. Some of the follicles may be empty and may not contain an egg at all. 






Thursday, 24 January 2019

Success in IVF Treatment




Lesley Brown was a patient with nine years of primary infertility who sought the assistance of Patrick Steptoe and Robert Edwards at the Oldham General Hospital in England in 1970’s. At that time, she was unaware of the historical revolution in IVF treatment she was going to be associated with. Fertilisation of oocytes outside the human body, a process known as in vitro fertilisation (IVF), was considered entirely experimental and unsuccessful around that period. 



Without using medications to stimulate her ovaries, Lesley Brown underwent laparoscopic egg retrieval, with her single egg fertilised in the laboratory, and later transferred back into the uterus. The embryo transfer resulted in the first live birth from IVF, a daughter Louise Brown, who was born in July 1978.

                          Read more @

Saturday, 29 December 2018

Secondary Infertility



What is secondary infertility?
 15 – 20 % of fertile women often experience difficulty in conceiving after a childbirth or an abortion. This condition is called secondary infertility and it affects a woman socially and emotionally. The causes of secondary infertility are also same as primary infertility but it confuses a woman who has already experienced a pregnancy.


How Changes in the lifestyle of partners affects fertility?
 Ovulatory disorders are primarily related to food and lifestyle. Eating polyunsaturated fats, less dietary fibers, carbohydrates with high glycemic index are key factors in causing diet related fertility disorders. These dietary factors often increase weight and subsequently leads alteration in hormone balance. With gain in weight the periods become irregular and the woman ends up with fertility problems. 



How male fertility profile can change with time?
Men continue to produce sperm throughout their lives, a man’s decrease in sperm characteristics occurs much later. Sperm quality deteriorates somewhat as men get older, but it generally does not become a problem before a man is in his 60s. there is no maximum age at which a man cannot father a child, as evidenced by men in their 60s and 70s conceiving with younger partners. However ageing men may develop medical illnesses that adversely affect their sexual and reproductive function. Alcohol, Obesity and diabetes can affect sperm quality which are acquired due to lifestyle changes over time. 


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Sunday, 2 December 2018

Declining Fertility and Consequences






What is Infertility?

Infertility is defined as the incapacity to fulfil pregnancy after a reasonable time of sexual intercourse with no contraceptive measures taken. It implies a deficiency that does not compromise the physical integrity of the individual, nor is it life-threatening. It may negatively impact the development of the individual, bringing about frustration and weakening the personality, since most couples consider having children as a vital objective. Infertility is a common problem affecting one couple in six.

Fertility efficiency in human being

As compared to other species, the human being is highly inefficient in terms of reproduction. The fertility rate per cycle is about 20% and the accumulated pregnancy rate in couples with proven fertility is ~90% after 12 months and 94% after 2 years. Delayed childbearing, alterations in semen quality due to habits such as cigarette smoking and alcohol, changes in sexual behaviour and eliminations of most taboos are some of the modifiable factors of infertility. The study of infertile couple has always been focussed on different factors: ovulatory factor (present in about 20% of couples), utero-tubal peritoneal factor (present in ~30% of couples), semen migration factor (10% of cases) and male factor (30% of couples). Around 40% of all infertile couples exhibit a combination of factors and about 15 % of couples may not display any objective alteration leading to a definite diagnosis.

Waiting period for conception

Fecundity is the probability of becoming pregnant in one particular menstrual cycle and is about 20%, depending on the age of the woman. This entails that the average time to develop pregnancy is around 4 months. The concept of "reasonable time" is debatable; the World Health Organisation (WHO, 1992a) as well as the European Society of Human Reproduction and Embryology (ESHRE, 1996) in their recommendations mention a 2year minimum deadline for developing pregnancy. Most physicians initiate study of an infertile couple following 1 year of failed pregnancy attempts. When the woman is >39 years, it might be advisable to begin the study after 6 months of unsuccessful attempts. The waiting time should be related to the age of the woman, the history of alterations that affect fertility, the desires and wishes of the couple.





Delayed decision for pregnancy and the consequences

There is an increase in the number of visits to infertility clinics in the last few years. This may be due to increased awareness and declining fertility. The average age at which women wish to become pregnant has increased due to postponement of the decision about pregnancy. Marital instability like divorce and seeking stability with new partners implies waiting longer before making the decision to have any children.
Alterations in semen quality can influence the need for advice on infertility. Habits such as cigarette smoking and alcohol abuse are harmful for semen quality. There have been changes in sexual behaviour like changing partners and use of proper contraception among younger couples. This may lead to higher incidence of sexually transmitted diseases (ST) to tubal–peritoneal infections that have consequences for fertility. Elimination of most taboos about fertility results in a higher frequency of visits by couples to the doctor.

A desire to become pregnant at ~40 years of age does not only entail a low possibility of success, but also an increased risk of developing maternal pregnancy ailments such as pre-eclampsia, hypertension and diabetes, as well as foetal chromosomal abnormalities and miscarriages.



  
The decline in femalefertility starts at 30 years of age and becomes more pronounced at 40.
The negative effect age has on the ovum is mainly its inefficacy to complete a normal first meiotic division and perhaps adequately to start the second meiosis In addition to ovum quality, age also affects the number of follicles available for ovulation.

In addition to age, other factors also affect follicular availability, such as genetic factors, chromosomal abnormalities, autoimmune diseases, smoking, ovarian surgery, endometriomas, chemotherapy, radiation therapy, pelvic adhesions, chlamydia exposure, and others. Many men with normal seminal parameters are infertile due to defects in the spermatic function. Several conditions are known to invoke alterations in the amount and quality of the sperm sample. These include varicocele, genital infections, trauma, surgeries, gene dysfunctions, toxic substances, etc. This situation occurs in about 30% of couples. Around 40% of all couples who seek help for infertility usually exhibit a combination of factors; i.e. a female factor combined with a male disorder.

Approximately 15% of couples, even when all the above factors have been considered, may not display any objective alterations leading to a definite diagnosis. They are then
classified as patients with unexplained infertility, at least at the time of the diagnosis.

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